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Rarely, serious side effects can occur. Choosing a medication to treat overweight or obesity is a decision between you and your health care professional.

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Important factors to consider include. How long you will need to take weight management medication depends on whether the drug helps you lose weight and keep it off and whether you experience serious side effects.

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If you have lost enough weight to improve your health and are not experiencing serious side effects, your health care professional may advise you to stay on the medication indefinitely. Your health care professional may also.

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Because obesity is a chronic disease, you may need to continue your new eating and physical activity habits and other behaviors for years-or even a lifetime-to improve your health and maintain a healthier weight. You probably will regain some weight after you stop taking weight management medication. Developing and maintaining healthy eating habits and increasing physical activity may help you regain less weight or keep it off.

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Federal physical activity guidelines You may need to do more than minutes of moderate-intensity activity a week to reach or maintain your weight-loss goal. Some, but not all, insurance plans cover medications that treat overweight and obesity.

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Contact your insurance provider to find out if your plan covers these medications. The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs-orlistat Xenical, Alliphentermine-topiramate Qsymianaltrexone-bupropion Contraveliraglutide Saxendaand semaglutide Wegovy -for long-term use.

A sixth approved drug, setmelanotide IMCIVREEis limited to people who have been diagnosed with one of three specific rare genetic disorders, which must be confirmed by genetic testing. You can keep taking these medications as long as you are benefiting from treatment and not experiencing serious side effects.

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Some weight management medications that curb appetite are approved by the FDA for short-term use only, for up to 12 weeks. Although some health care professionals prescribe them for longer periods, not many research studies have looked at how safe and effective they are for long-term use.

Never take weight management medications if you are pregnant.

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If you are planning to get pregnant, you should also avoid these medications, as some of them may harm the fetus. By choosing an off-label medication to treat overweight and obesity, your health care professional may prescribe.

You should feel comfortable asking whether your health care professional is prescribing a medication that is not approved for treating overweight and obesity. Before using a medication, learn all you need to know about it.

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Researchers are currently studying several new medications and combinations of medications in animals and people. Researchers are working to identify safer and more effective medications to help people who are overweight or have obesity lose weight and maintain a healthy weight for a long time. The NIDDK conducts and supports clinical trials in many diseases and conditions, including overweight and obesity. The trials look to find new ways to prevent, detect, or treat disease and improve quality of life.

Clinical trials-and other types of clinical studies -are part of medical research and involve people like you. When you volunteer to take part in a clinical study, you help health care professionals and researchers learn more about disease and improve health care for people in the future.

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Researchers are studying many cts of prescription medications to treat overweight or obesitysuch as. Find out if clinical studies are right for you.

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Watch a video of NIDDK Director Dr. Griffin P. Rodgers explaining the importance of participating in clinical trials. You can view a filtered list of clinical studies on prescription medications to treat overweight and obesity that are federally funded, open, and recruiting at www.

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You can expand or narrow the list to include clinical studies from industry, universities, and individuals; however, the NIH does not review these studies and cannot ensure they are safe. Always talk with your health care provider before you participate in a clinical study. This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases NIDDKpart of the National Institutes of Health.

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The NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by the NIDDK is carefully reviewed by NIDDK scientists and other experts.

The NIDDK would like to thank: Kishore Gadde, M. How common are overweight and obesity? How do weight management medications work?

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Who might benefit from weight management medications? Can children or teenagers take weight management medications?

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Can medications replace physical activity and healthy eating habits as a way to lose weight? What are the benefits of using prescription medications to lose weight?

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What are the concerns about using prescription medications to lose weight? Which weight management medication might work for me? How long will I need to take weight management medication? Will I regain some weight after I stop taking weight management medication? Will insurance cover the cost of weight management medication? What medications are available to treat overweight and obesity?

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What other medications for weight loss may be available in the future? Clinical Trials for Prescription Medications to Treat Overweight and Obesity What are overweight and obesity? com or follow him on Twitter and Facebook.

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It is a fact that thin girls destroy their beauty after substantial weight gain. There is no reason to present the worst version of yourself to the world. If you are like me, you must be devastated at how easily beauty can be taken away from the world.

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